Endocrine Abstracts

31 years old female presented to casualty with acute abdominal pain and vomiting. The physical findings showed acutely unwell female with persistent regular tachycardia and a large goitre with a bruit. There were no demonstrable eye signs indicating Grave’s disease. Initial investigation showed profound high anion gap metabolic acidosis (PH-7.13,HCO3-5.1, CL-113.6 BE-22.1PCO2 2.69,PO2-12.5) and severe hyperthyroidism (FT4-44 picomol per litre,FT3-24.8 picomol per litre,TS...

We present the case of a 49 year old man who initially presented to his GP with complaints of tiredness, weight gain and tingling in his right hand. GP requested thyroid hormone measurements which showed FT4 level of 3.4 picomoles per litre and TSH 10.89 milli international units per litre. The inappropriately low TSH level raised the possibility of central hypothyroidism and triggered further investigations which revealed a low level for GH, LH, FSH, testosterone and cortisol...